{"id":4400,"date":"2020-10-31T13:14:30","date_gmt":"2020-10-31T12:14:30","guid":{"rendered":"https:\/\/encore-expertisecentrum.nl\/?page_id=4400"},"modified":"2025-12-12T16:57:12","modified_gmt":"2025-12-12T15:57:12","slug":"camk2","status":"publish","type":"page","link":"https:\/\/encore-expertisecentrum.nl\/en\/publications\/camk2\/","title":{"rendered":"CAMK2 Syndrome"},"content":{"rendered":"

Publicaties CAMK2 Syndroom<\/span><\/i><\/a><\/h4><\/div>
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Gauger SJ, et al. (2024) CaMKII\u03b1 hub ligands are unable to reverse known phenotypes in Angelman syndrome mice.\u00a0<\/span><\/strong>Basic Clin Pharmacol Toxicol<\/span>.<\/em> Pubmed<\/a><\/p>\n

Cheung JS, et al. (2024) CAMK2; four genes, one syndrome? Delineation of genotype-phenotype correlations.\u00a0<\/span><\/strong>Curr Opin Neurobiol<\/span>.<\/em> Pubmed<\/a><\/p>\n

Rigter PMF, et.al. (2024) Role of CAMK2D in neurodevelopment and associated conditions.<\/strong> Am J Hum Genet. <\/em>Pubmed<\/a><\/span><\/p>\n

Rigter PMF, de Konink C, van Woerden GM. (2023). Loss of CAMK2G affects intrinsic and motor behavior but has minimal impact on cognitive behavior.<\/strong> Front Neurosci.<\/em> Jan 6;16:1086994. Pubmed<\/a><\/span><\/p>\n

Rigter PMF, et.al. (2022) Adult Camk2a<\/em> gene reinstatement restores the learning and plasticity deficits of Camk2a<\/em> knockout mice. <\/strong> Pubmed<\/a><\/span><\/p>\n

Dwyer BK, et.al. (2022) Case Report: Developmental Delay and Acute Neuropsychiatric Episodes Associated With a de novo<\/em> Mutation in the CAMK2B<\/em> Gene (c.328G>A p.Glu110Lys) <\/strong>Front Pharmacol.<\/em> 10;13:794008 Pubmed<\/a><\/span><\/p>\n

Onori MP & van Woerden GM. (2021) Role of calcium\/calmodulin-dependent kinase 2 in neurodevelopmental disorders. <\/strong>Brain Res Bull. <\/em>S0361-9230(21)00090-3 Pubmed<\/a><\/span><\/p>\n

Moro A, et.al.<\/em> (2020) CaMKll controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles. <\/strong>PLoS Biol.\u00a0<\/em>Pubmed<\/span><\/a><\/p>\n

Kool MJ, et al.<\/em> (2019) CAMK2-dependent signaling in neurons is essential for survival.<\/strong> J Neurosci<\/em>. 39; 5424\u201339. Pubmed<\/span><\/a><\/p>\n

Vargas JY, et al.<\/em> (2019) The Wnt\/Ca 2+ pathway is involved in interneuronal communication mediated by tunneling nanotubes.<\/em><\/strong> EMBO J<\/em>. Pubmed<\/span><\/a><\/p>\n

Onori MP, et al.<\/em> (2018) The intellectual disability-associated CAMK2G p.Arg292Pro mutation acts as a pathogenic gain-of-function.<\/strong> Hum Mutat.<\/em> 39; 2008\u201324. Pubmed<\/a><\/span><\/p>\n

K\u00fcry S, et al.<\/em> (2017) De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability.<\/strong> Am J Hum Genet.<\/em> 101; 768\u201388.\u00a0Pubmed<\/span><\/a><\/p>\n

Kool MJ, et.al. <\/em>(2016) The molecular, temporal and region-specific requirements of the beta isoform of Calcium\/Calmodulin-dependent protein kinase type 2 (CAMK2B) in mouse locomotion.<\/strong> Sci Rep. <\/em>Pubmed<\/span><\/a><\/p>\n

Achterberg KG, et al.<\/em> (2014) Temporal and region-specific requirements of \u03b1CaMKII in spatial and contextual learning.<\/strong> J Neurosci.<\/em> 34; 11180\u20137.\u00a0Pubmed<\/span><\/a><\/p>\n

Woerden G, et.al.<\/em> (2009) betaCaMKll<\/strong> controls the direction of plasticity at parallel fiber-Purkinje cell synapses. <\/strong>Nat Neurosci. <\/em>12(7); 823-5. Pubmed<\/span><\/a><\/p>\n

Hojjati M, et.al.<\/em> (2007) Kinase activity is not required for alphaCaMKll-dependent presynaptic plasticity at CA3-CA1 synapses. <\/strong>Nat Neurosci. <\/em>10(9); 1125-7. Pubmed<\/span><\/a><\/p>\n

Hansel C, et.al.<\/em> (2006) alphaCaMKll is essential for cerebellar LTD and motor learning. <\/strong>Neuron. <\/em>51(6); 835-43. Pubmed<\/span><\/a><\/p>\n

Elgersma Y, et.al. <\/em>(2004) Mouse genetic approaches to investigating calcium\/calmodulin-dependent protein kinase ll function in plasticity and cognition. <\/strong>J Neurosci. <\/em>24(39); 8410-5. Pubmed<\/span><\/a><\/p>\n

Elgersma Y, et.al. <\/em>(2002) Inhibitory autophosphorylation of CaMKll controls PSD association, plasticity and learning. <\/strong>Neuron. <\/em>36(3); 493-505. Pubmed<\/span><\/a><\/p>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"Publicaties CAMK2 Syndroom Gauger SJ, et al. (2024) CaMKII\u03b1 hub ligands are unable to reverse known phenotypes in Angelman syndrome mice.\u00a0Basic Clin Pharmacol Toxicol. Pubmed Cheung JS, et al. (2024) CAMK2; four genes, one syndrome? Delineation of genotype-phenotype correlations.\u00a0Curr Opin Neurobiol. Pubmed Rigter PMF, et.al. (2024) Role of CAMK2D in neurodevelopment and associated conditions. Am [...]","protected":false},"author":1,"featured_media":0,"parent":3957,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/pages\/4400"}],"collection":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/comments?post=4400"}],"version-history":[{"count":11,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/pages\/4400\/revisions"}],"predecessor-version":[{"id":5307,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/pages\/4400\/revisions\/5307"}],"up":[{"embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/pages\/3957"}],"wp:attachment":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/media?parent=4400"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}