{"id":4403,"date":"2020-10-31T13:14:37","date_gmt":"2020-10-31T12:14:37","guid":{"rendered":"https:\/\/encore-expertisecentrum.nl\/?page_id=4403"},"modified":"2020-11-30T14:11:41","modified_gmt":"2020-11-30T13:11:41","slug":"costello-cfc","status":"publish","type":"page","link":"https:\/\/encore-expertisecentrum.nl\/en\/publications\/costello-cfc\/","title":{"rendered":"Costello &#8211; CFC"},"content":{"rendered":"<div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"\"  ><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"vc_tta-container\" data-vc-action=\"collapse\"><div class=\"vc_general vc_tta vc_tta-accordion vc_tta-color-grey vc_tta-style-classic vc_tta-shape-rounded vc_tta-o-shape-group vc_tta-controls-align-left\"><div class=\"vc_tta-panels-container\"><div class=\"vc_tta-panels\"><div class=\"vc_tta-panel vc_active\" id=\"1588325715276-80d12435-d6f0\" data-vc-content=\".vc_tta-panel-body\"><div class=\"vc_tta-panel-heading\"><h4 class=\"vc_tta-panel-title vc_tta-controls-icon-position-left\"><a href=\"#1588325715276-80d12435-d6f0\" data-vc-accordion data-vc-container=\".vc_tta-container\"><span class=\"vc_tta-title-text\">Publicaties Costello\/CFC<\/span><i class=\"vc_tta-controls-icon vc_tta-controls-icon-plus\"><\/i><\/a><\/h4><\/div><div class=\"vc_tta-panel-body\">\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p><span lang=\"nl\">Gripp KW, <em>et al.<\/em> (2019) <\/span><strong>Costello Syndrome: Clinical phenotype, genotype, and management guidelines.<\/strong> <em>Am J Med Gent A.<\/em> 179 (9); 1725-1744.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31222966\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"text-decoration: underline;\">Pubmed<\/span><\/a><\/p>\n<p>Schreiber J, <em>et al.<\/em> (2017) <strong>Mechanisms underlying cognitive deficits in a mouse model for Costello Syndrome are distinct from other RASopathy mouse models.<\/strong> <em>Sci Rep.\u00a0<\/em><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28455524\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"text-decoration: underline;\">Pubmed<\/span><\/a><\/p>\n<p>Wang T, <em>et.al. <\/em>(2015) <strong>In vivo synaptic transmission and morphology in mouse models of tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome.<\/strong> <em>Front Cell Neurosci.\u00a0<\/em><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26190969\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"text-decoration: underline;\">Pubmed<\/span><\/a><\/p>\n<p>Beukers, W. <em>et al.<\/em> (2013) <strong>HRAS mutations in bladder cancer at an early age and the possible association with the Costello Syndrome.<\/strong> <em>Eur J Hum Genet<\/em> DOI: 10.1038\/ejhg.2013.251. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24169525\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"text-decoration: underline;\">Pubmed<\/span><\/a><\/p>\n<p>Krab, L.C. <em>et al.<\/em> (2008) <strong>Oncogenes on my mind: ERK and MTOR signaling in cognitive diseases. <\/strong><em>Trends Genet<\/em> 24, 498\u2013510. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18774199\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"text-decoration: underline;\">Pubmed<\/span><\/a><\/p>\n<p>Kushner, S.A. <em>et al.<\/em> (2005) <strong>Modulation of presynaptic plasticity and learning by the H-ras\/extracellular signal-regulated kinase\/synapsin I signaling pathway.<\/strong> <em>J Neurosci<\/em> 25, 9721\u20139734. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16237176\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"text-decoration: underline;\">Pubmed<\/span><\/a><\/p>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"Publicaties Costello\/CFC Gripp KW, et al. (2019) Costello Syndrome: Clinical phenotype, genotype, and management guidelines. Am J Med Gent A. 179 (9); 1725-1744.\u00a0Pubmed Schreiber J, et al. (2017) Mechanisms underlying cognitive deficits in a mouse model for Costello Syndrome are distinct from other RASopathy mouse models. Sci Rep.\u00a0Pubmed Wang T, et.al. (2015) In vivo synaptic [...]","protected":false},"author":1,"featured_media":0,"parent":3957,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/pages\/4403"}],"collection":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/comments?post=4403"}],"version-history":[{"count":6,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/pages\/4403\/revisions"}],"predecessor-version":[{"id":4759,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/pages\/4403\/revisions\/4759"}],"up":[{"embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/pages\/3957"}],"wp:attachment":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/media?parent=4403"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}