{"id":4649,"date":"2008-11-11T10:40:19","date_gmt":"2008-11-11T09:40:19","guid":{"rendered":"https:\/\/encore-expertisecentrum.nl\/?p=4649"},"modified":"2020-11-11T18:15:52","modified_gmt":"2020-11-11T17:15:52","slug":"nfsimva-trial","status":"publish","type":"post","link":"https:\/\/encore-expertisecentrum.nl\/en\/nfsimva-trial\/","title":{"rendered":"NFSIMVA TRIAL"},"content":{"rendered":"<p>Phase 3 clinical study of the effect of the drug Simvastatin in patients with NF1<\/p>\n\n\n\n<p>In this study, designed and conducted by our center of expertise, the effect of a 3 month treatment with the drug Simvastatin on cognition in children with NF1 was tested. A total of 62 participants took part. The study has been completed and the results were published:<\/p>\n\n\n\n<p>Krab, L.C. <em>et al.<\/em> (2008) <strong>Effect of simvastatin on cognitive functioning in children with neurofibromatosis type 1: a randomized controlled trial.<\/strong> <em>JAMA<\/em> 300, 287\u2013294. <span style=\"text-decoration: underline;\">Pubmed<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>Phase 3 clinical study of the effect of the drug Simvastatin in patients with NF1<\/p>","protected":false},"author":5,"featured_media":4684,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[48],"tags":[],"_links":{"self":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/posts\/4649"}],"collection":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/comments?post=4649"}],"version-history":[{"count":2,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/posts\/4649\/revisions"}],"predecessor-version":[{"id":4655,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/posts\/4649\/revisions\/4655"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/media\/4684"}],"wp:attachment":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/media?parent=4649"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/categories?post=4649"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/tags?post=4649"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}