{"id":4653,"date":"2013-11-11T10:42:42","date_gmt":"2013-11-11T09:42:42","guid":{"rendered":"https:\/\/encore-expertisecentrum.nl\/?p=4653"},"modified":"2020-11-11T18:15:35","modified_gmt":"2020-11-11T17:15:35","slug":"simcoda-trial","status":"publish","type":"post","link":"https:\/\/encore-expertisecentrum.nl\/en\/simcoda-trial\/","title":{"rendered":"SIMCODA TRIAL"},"content":{"rendered":"<p>Phase 3 clinical study of the effect of the drug Simvastatin in children with NF1<\/p>\n\n\n\n<p>In this study, designed and conducted by ENCORE, the effect of the drug Simvastatin on cognition was tested in children with NF1. A total of 84 participants took part, who were treated for a year. The study has been completed and the results were published:<\/p>\n\n\n\n<p>Van Der Vaart, T. <em>et al.<\/em> (2013) <strong>Simvastatin for cognitive deficits and behavioural problems in patients with neurofibromatosis type 1 (NF1-SIMCODA): a randomised, placebo-controlled trial.<\/strong> <em>Lancet Neurol<\/em> 12, 1076\u20131083. <span style=\"text-decoration: underline;\">Pubmed<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>Phase 3 clinical study of the effect of the drug Simvastatin in children with NF1<\/p>","protected":false},"author":5,"featured_media":4687,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[48],"tags":[],"_links":{"self":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/posts\/4653"}],"collection":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/comments?post=4653"}],"version-history":[{"count":1,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/posts\/4653\/revisions"}],"predecessor-version":[{"id":4654,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/posts\/4653\/revisions\/4654"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/media\/4687"}],"wp:attachment":[{"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/media?parent=4653"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/categories?post=4653"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/encore-expertisecentrum.nl\/en\/wp-json\/wp\/v2\/tags?post=4653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}